Nuchal translucency: an ultrasound marker for fetal chromosomal abnormalities
نویسندگان
چکیده
منابع مشابه
Nuchal translucency: an ultrasound marker for fetal chromosomal abnormalities.
CONTEXT The literature shows an association between several ultrasound markers and chromosome abnormality. Among these, measurement of nuchal translucency has been indicated as a screening method for aneuploidy. The trisomy of chromosome 21 has been most evaluated. OBJECTIVE To define the best fixed cutoff point for nuchal translucency, with the assistance of the ROC curve, and its accuracy i...
متن کاملMeasurement of Nuchal Translucency Thickness for Detection of Chromosomal Abnormalities using First Trimester Ultrasound Fetal Images
The Nuchal Translucency thickness measurement is made to identify the Down Syndrome in screening first trimester fetus and presented in this paper. The mean shift analysis and canny operators are utilized for segmenting the nuchal translucency region and the exact thickness has been estimated using Blob analysis. It is observed from the results that the fetus in the 14th week of Gestation is ex...
متن کاملFetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy.
OBJECTIVE To examine the significance of fetal nuchal translucency at 10-14 weeks' gestation in the prediction of abnormal fetal karyotype. DESIGN Prospective screening study. SETTING The Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London. SUBJECTS 827 fetuses undergoing first trimester karyotyping by amniocentesis or chorionic villus sampling. MAIN OU...
متن کاملIs high fetal nuchal translucency associated with submicroscopic chromosomal abnormalities on array CGH?
OBJECTIVE To examine the possible association between high fetal nuchal translucency thickness (NT) and pathogenic chromosomal copy number variants (CNVs) detected by array comparative genomic hybridization (CGH) in pregnancies with normal fetal karyotype. METHODS Array CGH was carried out in stored samples of chorionic villi from 215 singleton pregnancies resulting in live births in which ch...
متن کاملMeasurement of fetal nuchal translucency thickness by three-dimensional ultrasound.
OBJECTIVE To investigate the feasibility and repeatability of nuchal translucency thickness measurement using three-dimensional ultrasound. METHODS Forty consecutive women with uncomplicated singleton pregnancies attending for Down syndrome screening at 11-14 weeks' gestation were included in this prospective crossover trial. Nuchal translucency thickness was measured using both two-dimension...
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ژورنال
عنوان ژورنال: Sao Paulo Medical Journal
سال: 2001
ISSN: 1516-3180
DOI: 10.1590/s1516-31802001000100006